Human EPHA6 protein (Recombinant-Active) (C-10*His) (STJP012310)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human EPHA6-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. When rhEphA6 is Immobilised at 2 Mu g/mL, 100 Mu L/well, it binds biotinylated rhEphrin-A3 with a linear range of 0.31-20 ng/mL. |
Target Information
| Gene Symbol | EPHA6 |
| Gene ID | 285220 |
| Uniprot ID | EPHA6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Trp23-Val550 |
Additional Info
| Function | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin Type-A Receptor 6Eph Homology Kinase 2Ehk-2Eph-Like Kinase 12Ek12 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Ephrin Type-A Receptor 6 proteinEph Homology Kinase 2 proteinEhk-2 proteinEph-Like Kinase 12 proteinEk12 proteinEPHA6 proteinEHK2 proteinHEK12 protein |
Information sourced from Uniprot.org