Human Endomucin protein (Recombinant) (His-Tag) (STJP017741)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Endomucin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 100mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EMCN |
| Gene ID | 51705 |
| Uniprot ID | MUCEN_HUMAN |
| Accession Number | NP_057326 |
| Immunogen | Human |
| Immunogen Region | 19-190aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in heart, kidney and lung. |
| Post Translational Modifications | Highly O-glycosylated. Sialic acid-rich glycoprotein. |
| Function | Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. |
| Protein Name | EndomucinEndomucin-2Gastric Cancer Antigen Ga34Mucin-14Muc-14 |
| Database Links | |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinMembraneConsistently Localized To The Plasma Membrane And Less Abundantly To Golgi-Like Perinuclear StacksIsoform 2: Secreted |
| Alternative Protein Names | Endomucin proteinEndomucin-2 proteinGastric Cancer Antigen Ga34 proteinMucin-14 proteinMuc-14 proteinEMCN proteinEMCN2 proteinMUC14 protein |
Information sourced from Uniprot.org