Human ELOVL6 protein (Recombinant) (N-GST & C-His) (STJP016086)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ELOVL6-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | ELOVL6 |
| Gene ID | 79071 |
| Uniprot ID | ELOV6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn2-Ser33&Leu89-Lys136 |
Additional Info
| Post Translational Modifications | N-Glycosylated. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Very Long Chain Fatty Acid Elongase 63-Keto Acyl-Coa Synthase Elovl6Elovl Fatty Acid Elongase 6Elovl Fa Elongase 6Elongation Of Very Long Chain Fatty Acids Protein 6Fatty Acid Elongase 2Helo2Fatty Acyl-Coa ElongaseLong-Chain Fatty-Acyl ElongaseVery Long Chain 3-Ketoacyl-Coa Synthase 6Very Long Chain 3-Oxoacyl-Coa Synthase 6 |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Very Long Chain Fatty Acid Elongase 6 protein3-Keto Acyl-Coa Synthase Elovl6 proteinElovl Fatty Acid Elongase 6 proteinElovl Fa Elongase 6 proteinElongation Of Very Long Chain Fatty Acids Protein 6 proteinFatty Acid Elongase 2 proteinHelo2 proteinFatty Acyl-Coa Elongase proteinLong-Chain Fatty-Acyl Elongase proteinVery Long Chain 3-Ketoacyl-Coa Synthase 6 proteinVery Long Chain 3-Oxoacyl-Coa Synthase 6 proteinELOVL6 proteinFACE proteinLCE protein |
Information sourced from Uniprot.org