Human ELAC1 protein (Recombinant) (His-Tag) (STJP019186)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP019186
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General Information

Short DescriptionRecombinant-Human ELAC1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolELAC1
Gene ID55520
Uniprot IDRNZ1_HUMAN
Accession NumberNP_061166
ImmunogenHuman
Immunogen Region1-363aa
Immunogen SequenceMSMDVTF LGTGAAYPSP TRGASAVVLR CEGECWLFDC GEGTQTQLMK SQLKAGRITK IFITHLHGDH FFGLPGLLCT ISLQSGSMVS KQPIEIYGPV GLRDFIWRTM ELSHTELVFH YVVHELVPTA DQCPAEELKE FAHVNRADSP PKEEQGRTIL LDSEENSYLL FDDEQFVVKA FRLFHRIPSF GFSVVEKKRP GKLNAQ

Additional Info

Tissue Specificity Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Function Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1.
Protein Name Zinc Phosphodiesterase Elac Protein 1
Deleted In Ma29
Elac Homolog Protein 1
Ribonuclease Z 1
Rnase Z 1
Trna 3 Endonuclease 1
Trnase Z 1
Database Links
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Mainly Cytosolic
Alternative Protein Names Zinc Phosphodiesterase Elac Protein 1 protein
Deleted In Ma29 protein
Elac Homolog Protein 1 protein
Ribonuclease Z 1 protein
Rnase Z 1 protein
Trna 3 Endonuclease 1 protein
Trnase Z 1 protein
ELAC1 protein
D29 protein

Information sourced from Uniprot.org

Citations

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