Human eIF-4H/EIF4H protein (Recombinant) (His-Tag) (STJP017672)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human eIF-4H/EIF4H-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EIF4H |
| Gene ID | 7458 |
| Uniprot ID | IF4H_HUMAN |
| Accession Number | NP_071496 |
| Immunogen | Human |
| Immunogen Region | 1-248aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | The short isoform is the predominant isoform and is expressed alone in liver and skeletal muscle. Both isoforms are expressed in fibroblast, spleen, testis and bone marrow. Levels are high in lung and pancreas and low in heart, frontal cortex and kidney. |
| Function | Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA. |
| Protein Name | Eukaryotic Translation Initiation Factor 4hEif-4hWilliams-Beuren Syndrome Chromosomal Region 1 Protein |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-72649Reactome: R-HSA-72662Reactome: R-HSA-72702Reactome: R-HSA-72706 |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Protein Names | Eukaryotic Translation Initiation Factor 4h proteinEif-4h proteinWilliams-Beuren Syndrome Chromosomal Region 1 Protein proteinEIF4H proteinKIAA0038 proteinWBSCR1 proteinWSCR1 protein |
Information sourced from Uniprot.org