Human EFNB3 protein (Recombinant) (N-His-SUMO) (STJP009037)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human EFNB3-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | EFNB3 |
| Gene ID | 1949 |
| Uniprot ID | EFNB3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn36-His133 |
Additional Info
| Function | Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. (Microbial infection) Acts as a receptor for nipah virus and hendra virus. |
| Protein Name | Ephrin-B3Eph-Related Receptor Transmembrane Ligand Elk-L3Eph-Related Receptor Tyrosine Kinase Ligand 8Lerk-8 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928662Reactome: R-HSA-3928664Reactome: R-HSA-3928665 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Ephrin-B3 proteinEph-Related Receptor Transmembrane Ligand Elk-L3 proteinEph-Related Receptor Tyrosine Kinase Ligand 8 proteinLerk-8 proteinEFNB3 proteinEPLG8 proteinLERK8 protein |
Information sourced from Uniprot.org