Human EF-1 beta/EEF1B2 protein (Recombinant) (His-Tag) (STJP017083)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human EF-1 beta/EEF1B2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 100mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EEF1B2 |
| Gene ID | 1933 |
| Uniprot ID | EF1B_HUMAN |
| Accession Number | NP_066944 |
| Immunogen | Human |
| Immunogen Region | 1-225aa |
| Immunogen Sequence | MGFGDLKSPA GLQVLNDYLA DKSYIEGYVP SQADVAVFEA VSSPPPADLC HALRWYNHIK SYEKEKASLP GVKKALGKYG PADVEDTTGS GATDSKDDDD IDLFGSDDEE ESEEAKRLRE ERLAQYESKK AKKPALVAKS SILLDVKPWD DETDMAKLEE CVRSIQADGL VWGSSKLVPV GYGIKKLQIQ CVVEDDKVGT DMLEEQITAF EDYVQSMDVA AFNKI |
Additional Info
| Post Translational Modifications | Phosphorylation affects the GDP/GTP exchange rate. |
| Function | Catalytic subunit of the guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) of the eukaryotic elongation factor 1 complex (eEF1). Stimulates the exchange of GDP for GTP on elongation factor 1A (eEF1A), probably by displacing GDP from the nucleotide binding pocket in eEF1A. |
| Protein Name | Elongation Factor 1-BetaEf-1-BetaEef-1b Alpha |
| Database Links | Reactome: R-HSA-156842 |
| Cellular Localisation | |
| Alternative Protein Names | Elongation Factor 1-Beta proteinEf-1-Beta proteinEef-1b Alpha proteinEEF1B2 proteinEEF1B proteinEF1B protein |
Information sourced from Uniprot.org