Human EDAR protein (Recombinant) (N-His) (STJP006209)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human EDAR-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | EDAR |
| Gene ID | 10913 |
| Uniprot ID | EDAR_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys212-Ser448 |
Additional Info
| Function | Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member EdarAnhidrotic Ectodysplasin Receptor 1Downless HomologEda-A1 ReceptorEctodermal Dysplasia ReceptorEctodysplasin-A Receptor |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member Edar proteinAnhidrotic Ectodysplasin Receptor 1 proteinDownless Homolog proteinEda-A1 Receptor proteinEctodermal Dysplasia Receptor proteinEctodysplasin-A Receptor proteinEDAR proteinDL protein |
Information sourced from Uniprot.org