Human EAAT4 (Excitatory Amino Acid Transporter 4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014933)
SPECIFICATIONS
General Information
| Short Description | This EAAT4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.129ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | SLC1A6 |
| Gene ID | 6511 |
| Uniprot ID | EAA4_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Brain, mainly in the cerebellum. Expressed densely and selectively in cell bodies of Purkinje cells. |
| Post Translational Modifications | |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). |
| Protein Name | Excitatory Amino Acid Transporter 4Sodium-Dependent Glutamate/Aspartate TransporterSolute Carrier Family 1 Member 6 |
| Database Links | Reactome: R-HSA-210500Reactome: R-HSA-425393 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Excitatory Amino Acid Transporter 4 ELISA kitSodium-Dependent Glutamate/Aspartate Transporter ELISA kitSolute Carrier Family 1 Member 6 ELISA kitSLC1A6 ELISA kitEAAT4 ELISA kit |
| output |
Information sourced from Uniprot.org