Human EAAT1 (Excitatory Amino Acid Transporter 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014928)
SPECIFICATIONS
General Information
| Short Description | This EAAT1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.123ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | SLC1A3 |
| Gene ID | 6507 |
| Uniprot ID | EAA1_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in brain. Detected at very much lower levels in heart, lung, placenta and skeletal muscle. Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia. |
| Post Translational Modifications | Glycosylated. |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. |
| Protein Name | Excitatory Amino Acid Transporter 1Sodium-Dependent Glutamate/Aspartate Transporter 1Glast-1Solute Carrier Family 1 Member 3 |
| Database Links | Reactome: R-HSA-210455Reactome: R-HSA-210500Reactome: R-HSA-425393Reactome: R-HSA-5619062 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Excitatory Amino Acid Transporter 1 ELISA kitSodium-Dependent Glutamate/Aspartate Transporter 1 ELISA kitGlast-1 ELISA kitSolute Carrier Family 1 Member 3 ELISA kitSLC1A3 ELISA kitEAAT1 ELISA kitGLAST ELISA kitGLAST1 ELISA kit |
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Information sourced from Uniprot.org