| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTCCGCGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters. |
| Protein Name | Transcription Factor E2f3E2f-3 |
| Database Links | Reactome: R-HSA-1912408Reactome: R-HSA-2559580Reactome: R-HSA-2559585Reactome: R-HSA-68911Reactome: R-HSA-69231Reactome: R-HSA-9661069 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Transcription Factor E2f3 ELISA kitE2f-3 ELISA kitE2F3 ELISA kitKIAA0075 ELISA kit |
| output | |
Information sourced from Uniprot.org