Human DYNLT3 protein (Recombinant) (His-Tag) (STJP017800)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DYNLT3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DYNLT3 |
| Gene ID | 6990 |
| Uniprot ID | DYLT3_HUMAN |
| Accession Number | NP_006511 |
| Immunogen | Human |
| Immunogen Region | 1-116aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEEYHRH CDEVGFNAEE AHNIVKECVD GVLGGEDYNH NNINQWTASI VEQSLTHLVK LGKAYKYIVT CAVVQKSAYG FHTASSCFWD TTSDGTCTVR WENRTMNCIV NVFAIAIVL |
Additional Info
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. |
| Protein Name | Dynein Light Chain Tctex-Type 3Protein 91/23T-Complex-Associated Testis-Expressed 1-Like |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoskeletonChromosomeCentromereKinetochoreColocalizes With Bub3 At Kinetochores Specifically During Prometaphase |
| Alternative Protein Names | Dynein Light Chain Tctex-Type 3 proteinProtein 91/23 proteinT-Complex-Associated Testis-Expressed 1-Like proteinDYNLT3 proteinTCTE1L proteinTCTE1XL protein |
Information sourced from Uniprot.org