Human DYNLRB2 protein (Recombinant) (His-Tag) (STJP017099)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DYNLRB2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DYNLRB2 |
| Gene ID | 83657 |
| Uniprot ID | DLRB2_HUMAN |
| Accession Number | NP_570967 |
| Immunogen | Human |
| Immunogen Region | 1-96aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAEVEETLKR IQSHKGVIGT MVVNAEGIPI RTTLDNSTTV QYAGLLHHLT MKAKSTVRDI DPQNDLTFLR IRSKKHEIMV APDKEYLLIV IQNPCE |
Additional Info
| Tissue Specificity | High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine.moderate in kidney, pancreas, spleen, testis, ovary and colon.low in lung, liver, thymus and leukocyte. |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
| Protein Name | Dynein Light Chain Roadblock-Type 2Dynein Light Chain 2b - CytoplasmicRoadblock Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Protein Names | Dynein Light Chain Roadblock-Type 2 proteinDynein Light Chain 2b - Cytoplasmic proteinRoadblock Domain-Containing Protein 2 proteinDYNLRB2 proteinDNCL2B proteinDNLC2B proteinROBLD2 protein |
Information sourced from Uniprot.org