Human DYNLRB1 protein (Recombinant) (His-Tag) (STJP016794)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DYNLRB1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DYNLRB1 |
| Gene ID | 83658 |
| Uniprot ID | DLRB1_HUMAN |
| Accession Number | NP_054902 |
| Immunogen | Human |
| Immunogen Region | 1-96aa |
| Immunogen Sequence | MAEVEETLKR LQSQKGVQGI IVVNTEGIPI KSTMDNPTTT QYASLMHSFI LKARSTVRDI DPQNDLTFLR IRSKKNEIMV APDKDYFLIV IQNPTE |
Additional Info
| Tissue Specificity | High expression in heart, liver, brain and pancreas.moderate in placenta, skeletal muscle and kidney.low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
| Protein Name | Dynein Light Chain Roadblock-Type 1Bithoraxoid-Like ProteinBlpDynein Light Chain 2a - CytoplasmicDynein-Associated Protein Km23Roadblock Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Protein Names | Dynein Light Chain Roadblock-Type 1 proteinBithoraxoid-Like Protein proteinBlp proteinDynein Light Chain 2a - Cytoplasmic proteinDynein-Associated Protein Km23 proteinRoadblock Domain-Containing Protein 1 proteinDYNLRB1 proteinBITH proteinDNCL2A proteinDNLC2A proteinROBLD1 proteinHSPC162 protein |
Information sourced from Uniprot.org