| Short Description : | Recombinant-Human DYNLL2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% Glycerol, 0.2M NaCl |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DYNLL2 |
| Gene ID: | 140735 |
| Uniprot ID: | DYL2_HUMAN |
| Accession Number: | NP_542408 |
| Immunogen: | Human |
| Immunogen Region: | 1-89aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MSDRKAVIKN ADMSEDMQQD AVDCATQAME KYNIEKDIAA YIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. |
| Protein Name | Dynein Light Chain 2 - Cytoplasmic8 Kda Dynein Light Chain BDlc8bDynein Light Chain Lc8-Type 2 |
| Database Links | Reactome: R-HSA-139910Reactome: R-HSA-141444Reactome: R-HSA-1632852Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-3371497Reactome: R-HSA-5620924Reactome: R-HSA-5663220Reactome: R-HSA-6807878Reactome: R-HSA-6811436Reactome: R-HSA-68877Reactome: R-HSA-9609690Reactome: R-HSA-9646399Reactome: R-HSA-9648025 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Protein Names | Dynein Light Chain 2 - Cytoplasmic protein8 Kda Dynein Light Chain B proteinDlc8b proteinDynein Light Chain Lc8-Type 2 proteinDYNLL2 proteinDLC2 protein |
Information sourced from Uniprot.org
