Human DUSP23 protein (Recombinant) (His-Tag) (STJP017421)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017421
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General Information

Short DescriptionRecombinant-Human DUSP23-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% Glycerol, 100mM NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolDUSP23
Gene ID54935
Uniprot IDDUS23_HUMAN
Accession NumberNP_060293
ImmunogenHuman
Immunogen Region1-150aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK

Additional Info

Tissue Specificity Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.
Function Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
Protein Name Dual Specificity Protein Phosphatase 23
Low Molecular Mass Dual Specificity Phosphatase 3
Ldp-3
Vh1-Like Phosphatase Z
Database Links
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Mainly Cytosolic
Also Nuclear
Alternative Protein Names Dual Specificity Protein Phosphatase 23 protein
Low Molecular Mass Dual Specificity Phosphatase 3 protein
Ldp-3 protein
Vh1-Like Phosphatase Z protein
DUSP23 protein
LDP3 protein
VHZ protein

Information sourced from Uniprot.org

Citations

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