Human DUSP18 protein (Recombinant) (His-Tag) (STJP019320)

Name: Human DUSP18 protein (Recombinant) (His-Tag) (STJP019320)
SKU: STJP019320
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP019320

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Short Description	Recombinant-Human DUSP18-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE/Enzyme Activity
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% Glycerol, 0.1mM PMSF, 1mM EDTA
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Immunoreactivity	Specific activity is > 300unit/mg, and is defined as the amount of enzyme that hydrolyze 1.0nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37C

Gene Symbol	DUSP18
Gene ID	150290
Uniprot ID	DUS18_HUMAN
Accession Number	NP_689724
Immunogen	Human
Immunogen Region	1-188aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MGSHMTAPSC AFPVQFRQPS VSGLSQITKS LYISNGVAAN NKLMLSSNQI TMVINVSVEV VNTLYEDIQY MQVPVADSPN SRLCDFFDPI ADHIHSVEMK QGRTLLHCAA GVSRSAALCL AYLMKYHAMS LLDAHTWTKS CRPIIRPNSG FWEQLIHYEF QLFGKNTVHM VSSPVGMIPD IYEKEVRLMI PL

Tissue Specificity	Widely expressed with highest levels in liver, brain, ovary and testis.
Function	Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP).
Protein Name	Dual Specificity Protein Phosphatase 18 Low Molecular Weight Dual Specificity Phosphatase 20 Lmw-Dsp20
Database Links
Cellular Localisation	Cytoplasm Nucleus Mitochondrion Inner Membrane Peripheral Membrane Protein Intermembrane Side Translocates To Cytoplasm In Response To Apoptotic Stimuli Such As Staurosporine Treatment
Alternative Protein Names	Dual Specificity Protein Phosphatase 18 protein Low Molecular Weight Dual Specificity Phosphatase 20 protein Lmw-Dsp20 protein DUSP18 protein LMWDSP20 protein

Information sourced from Uniprot.org