Human DUSP10 protein (Recombinant) (His-Tag) (STJP017515)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DUSP10-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% Glycerol, 200mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 600unit/mg, and is defined as the amount of enzyme that hydrolyze 1.0nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37C. |
Target Information
| Gene Symbol | DUSP10 |
| Gene ID | 11221 |
| Uniprot ID | DUS10_HUMAN |
| Accession Number | NP_009138 |
| Immunogen | Human |
| Immunogen Region | 149-482aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in keratinocytes (at protein level). Detected in brain. |
| Function | Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38. |
| Protein Name | Dual Specificity Protein Phosphatase 10Mitogen-Activated Protein Kinase Phosphatase 5Map Kinase Phosphatase 5Mkp-5 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221Reactome: R-HSA-9652817 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Dual Specificity Protein Phosphatase 10 proteinMitogen-Activated Protein Kinase Phosphatase 5 proteinMap Kinase Phosphatase 5 proteinMkp-5 proteinDUSP10 proteinMKP5 protein |
Information sourced from Uniprot.org