| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.114ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This DSE Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | DSE |
| Gene ID: | 29940 |
| Uniprot ID: | DSE_HUMAN |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Expressed in squamous cell carcinomas (SCC), glioma, and some adenocarcinoma cell lines, but not in breast cancer cell lines or any normal tissues (at protein level). |
| Post Translational Modifications | N-glycosylated. Glycosylation is important for enzymatic activity. |
| Function | Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. Plays an important role in the biosynthesis of the glycosaminoglycan/mucopolysaccharide dermatan sulfate. |
| Protein Name | Dermatan-Sulfate Epimerase Ds Epimerase Chondroitin-Glucuronate 5-Epimerase Squamous Cell Carcinoma Antigen Recognized By T-Cells 2 Sart-2 |
| Database Links | Reactome: R-HSA-2022923 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Golgi Apparatus Membrane Cytoplasmic Vesicle Membrane Microsome Membrane |
| Alternative ELISA Names | Dermatan-Sulfate Epimerase ELISA kit Ds Epimerase ELISA kit Chondroitin-Glucuronate 5-Epimerase ELISA kit Squamous Cell Carcinoma Antigen Recognized By T-Cells 2 ELISA kit Sart-2 ELISA kit DSE ELISA kit SART2 ELISA kit |
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Information sourced from Uniprot.org
