Human DSC1 (Desmocollin 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014890)
SPECIFICATIONS
General Information
| Short Description | This DSC1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.057ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | DSC1 |
| Gene ID | 1823 |
| Uniprot ID | DSC1_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Strongly expressed in epidermis, less in lymph node and tongue. |
| Post Translational Modifications | |
| Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood. |
| Protein Name | Desmocollin-1Cadherin Family Member 1Desmosomal Glycoprotein 2/3Dg2/Dg3 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative ELISA Names | Desmocollin-1 ELISA kitCadherin Family Member 1 ELISA kitDesmosomal Glycoprotein 2/3 ELISA kitDg2/Dg3 ELISA kitDSC1 ELISA kitCDHF1 ELISA kit |
| output |
Information sourced from Uniprot.org