Human DNTTIP1 protein (Recombinant) (His-Tag) (STJP018441)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DNTTIP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNTTIP1 |
| Gene ID | 116092 |
| Uniprot ID | TDIF1_HUMAN |
| Accession Number | NP_443183 |
| Immunogen | Human |
| Immunogen Region | 1-329aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMGATGDA EQPRGPSGAE RGGLELGDAG AAGQLVLTNP WNIMIKHRQV QRRGRRSQMT TSFTDPAISM DLLRAVLQPS INEEIQTVFN KYMKFFQKAA LNVRDNVGEE VDAEQLIQEA CRSCLEQAKL LFSDGEKVIP RLTHELPGIK RGRQAEEECA HRGSPLPKKR KGRPPGHILS SDRAAAGMVW KPKSCEPIRR EGPKWDPA |
Additional Info
| Function | Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes.may recruit HDAC1 complexes to nucleosomes or naked DNA. |
| Protein Name | Deoxynucleotidyltransferase Terminal-Interacting Protein 1Terminal Deoxynucleotidyltransferase-Interacting Factor 1Tdif1Tdt-Interacting Factor 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Deoxynucleotidyltransferase Terminal-Interacting Protein 1 proteinTerminal Deoxynucleotidyltransferase-Interacting Factor 1 proteinTdif1 proteinTdt-Interacting Factor 1 proteinDNTTIP1 proteinC20orf167 proteinTDIF1 protein |
Information sourced from Uniprot.org