Human DNAJC24 protein (Recombinant) (His-Tag) (STJP018218)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DNAJC24-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAJC24 |
| Gene ID | 120526 |
| Uniprot ID | DJC24_HUMAN |
| Accession Number | NP_859057 |
| Immunogen | Human |
| Immunogen Region | 1-149aa |
| Immunogen Sequence |
Additional Info
| Function | Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). |
| Protein Name | Dnaj Homolog Subfamily C Member 24Csl-Type Zinc Finger-Containing Protein 3Diphthamide Biosynthesis Protein 4 |
| Database Links | Reactome: R-HSA-5358493 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Protein Names | Dnaj Homolog Subfamily C Member 24 proteinCsl-Type Zinc Finger-Containing Protein 3 proteinDiphthamide Biosynthesis Protein 4 proteinDNAJC24 proteinDPH4 proteinZCSL3 protein |
Information sourced from Uniprot.org