Human DNAJA1 protein (Recombinant) (N-His) (STJP008255)

Name: Human DNAJA1 protein (Recombinant) (N-His) (STJP008255)
SKU: STJP008255
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP008255

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Short Description	Recombinant-Human DNAJA1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as a co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV.
Protein Name	Dnaj Homolog Subfamily A Member 1 Dnaj Protein Homolog 2 Hsdj Heat Shock 40 Kda Protein 4 Heat Shock Protein J2 Hsj-2 Human Dnaj Protein 2 Hdj-2
Database Links	Reactome: R-HSA-3371497 Reactome: R-HSA-9841251
Cellular Localisation	Membrane Lipid-Anchor Cytoplasm Microsome Nucleus Perinuclear Region Mitochondrion Primarily Associated With Microsomes A Minor Proportion Is Associated With Mitochondria Primarily Cytoplasmic A Minor Proportion Is Associated With Nuclei
Alternative Protein Names	Dnaj Homolog Subfamily A Member 1 protein Dnaj Protein Homolog 2 protein Hsdj protein Heat Shock 40 Kda Protein 4 protein Heat Shock Protein J2 protein Hsj-2 protein Human Dnaj Protein 2 protein Hdj-2 protein DNAJA1 protein DNAJ2 protein HDJ2 protein HSJ2 protein HSPF4 protein

Information sourced from Uniprot.org