Human DLGAP5 protein (Recombinant) (N-His) (STJP015936)

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STJP015936
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Short Description :Recombinant-Human DLGAP5-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:DLGAP5
Gene ID:9787
Uniprot ID:DLGP5_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Gly429-Trp535
Post Translational Modifications Ubiquitinated, leading to its degradation. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.
Function Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Protein Name Disks Large-Associated Protein 5
Dap-5
Discs Large Homolog 7
Disks Large-Associated Protein Dlg7
Hepatoma Up-Regulated Protein
Hurp
Database Links Reactome: R-HSA-9013508
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Spindle
Localizes To The Spindle In Mitotic Cells
Colocalizes With Cdh1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells
Alternative Protein Names Disks Large-Associated Protein 5 protein
Dap-5 protein
Discs Large Homolog 7 protein
Disks Large-Associated Protein Dlg7 protein
Hepatoma Up-Regulated Protein protein
Hurp protein
DLGAP5 protein
DLG7 protein
KIAA0008 protein

Information sourced from Uniprot.org