Human DJ-1/PARK7 protein (Recombinant) (His-Tag) (STJP019735)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DJ-1/PARK7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM EDTA, 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R14A |
| Gene ID | 94274 |
| Uniprot ID | PP14A_HUMAN |
| Accession Number | NP_150281 |
| Immunogen | Human |
| Immunogen Region | 1-147aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. |
| Function | Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14a17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1Protein Kinase C-Potentiated Inhibitor Protein Of 17 KdaCpi-17 |
| Database Links | Reactome: R-HSA-5625740 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Protein Phosphatase 1 Regulatory Subunit 14a protein17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1 proteinProtein Kinase C-Potentiated Inhibitor Protein Of 17 Kda proteinCpi-17 proteinPPP1R14A proteinCPI17 proteinPPP1INL protein |
Information sourced from Uniprot.org