Human DHRS9 protein (Recombinant) (His-Tag) (STJP017466)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DHRS9-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DHRS9 |
| Gene ID | 10170 |
| Uniprot ID | DHRS9_HUMAN |
| Accession Number | NP_005762 |
| Immunogen | Human |
| Immunogen Region | 18-319aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMRKGKL KIEDITDKYI FITGCDSGFG NLAARTFDKK GFHVIAACLT ESGSTALKAE TSERLRTVLL DVTDPENVKR TAQWVKNQVG EKGLWGLINN AGVPGVLAPT DWLTLEDYRE PIEVNLFGLI SVTLNMLPLV KKAQGRVINV SSVGGRLAIV GGGYTPSKYA VEGFNDSLRR DMKAFGVHVS CIEPGLFKTN LADPVKVI |
Additional Info
| Tissue Specificity | Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node. |
| Function | 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Also plays a role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH. |
| Protein Name | Dehydrogenase/Reductase Sdr Family Member 93-Alpha Hydroxysteroid Dehydrogenase3-Alpha-HsdNadp-Dependent Retinol Dehydrogenase/ReductaseRdh-E2RdhlRetinol Dehydrogenase 15Short Chain Dehydrogenase/Reductase Family 9c Member 4Short-Chain Dehydrogenase/Reductase Retsdr8Tracheobronchial Epithelial Cell-Specific Retinol DehydrogenaseRdh-Tbe |
| Database Links | Reactome: R-HSA-2453902Reactome: R-HSA-5365859 |
| Cellular Localisation | Microsome MembraneEndoplasmic Reticulum MembraneAssociated With Microsomal Membranes |
| Alternative Protein Names | Dehydrogenase/Reductase Sdr Family Member 9 protein3-Alpha Hydroxysteroid Dehydrogenase protein3-Alpha-Hsd proteinNadp-Dependent Retinol Dehydrogenase/Reductase proteinRdh-E2 proteinRdhl proteinRetinol Dehydrogenase 15 proteinShort Chain Dehydrogenase/Reductase Family 9c Member 4 proteinShort-Chain Dehydrogenase/Reductase Retsdr8 proteinTracheobronchial Epithelial Cell-Specific Retinol Dehydrogenase proteinRdh-Tbe proteinDHRS9 proteinRDH15 proteinSDR9C4 proteinUNQ835 proteinPRO1773 protein |
Information sourced from Uniprot.org