Human DHPS protein (Recombinant) (His-Tag) (STJP016641)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DHPS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DHPS |
| Gene ID | 1725 |
| Uniprot ID | DHYS_HUMAN |
| Accession Number | NP_001921.1 |
| Immunogen | Human |
| Immunogen Region | 1-369aa |
| Immunogen Sequence |
Additional Info
| Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. |
| Protein Name | Deoxyhypusine SynthaseDhs |
| Database Links | Reactome: R-HSA-204626 |
| Cellular Localisation | |
| Alternative Protein Names | Deoxyhypusine Synthase proteinDhs proteinDHPS proteinDS protein |
Information sourced from Uniprot.org