Human DGKE protein (Recombinant) (N-His) (STJP004897)

Name: Human DGKE protein (Recombinant) (N-His) (STJP004897)
SKU: STJP004897
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP004897

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Short Description	Recombinant-Human DGKE-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Displays specificity for diacylglycerol substrates with an arachidonoyl acyl chain at the sn-2 position, with the highest activity toward 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol the main diacylglycerol intermediate within the phosphatidylinositol turnover cycle. Can also phosphorylate diacylglycerol substrates with a linoleoyl acyl chain at the sn-2 position but much less efficiently.
Protein Name	Diacylglycerol Kinase Epsilon Dag Kinase Epsilon Diglyceride Kinase Epsilon Dgk-Epsilon
Database Links	Reactome: R-HSA-114508
Cellular Localisation	Membrane Single-Pass Membrane Protein Cytoplasm
Alternative Protein Names	Diacylglycerol Kinase Epsilon protein Dag Kinase Epsilon protein Diglyceride Kinase Epsilon protein Dgk-Epsilon protein DGKE protein DAGK5 protein

Information sourced from Uniprot.org