Human delta Sarcoglycan/SGCD protein (Recombinant) (His-Tag) (STJP018087)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018087
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General Information

Short DescriptionRecombinant-Human delta Sarcoglycan/SGCD-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSGCD
Gene ID6444
Uniprot IDSGCD_HUMAN
Accession NumberNP_001121681
ImmunogenHuman
Immunogen Region57-289aa
Immunogen SequenceKVMNFT IDGMGNLRIT EKGLKLEGDS EFLQPLYAKE IQSRPGNALY FKSARNVTVN ILNDQTKVLT QLITGPKAVE AYGKKFEVKT VSGKLLFSAD NNEVVVGAER LRVLGAEGTV FPKSIETPNV RADPFKELRL ESPTRSLVME APKGVEINAE AGNMEATCRT ELRLESKDGE IKLDAAKIRL PRLPHGSYTP TGTRQK

Additional Info

Tissue Specificity Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
Post Translational Modifications Glycosylated. Disulfide bonds are present.
Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Protein Name Delta-Sarcoglycan
Delta-Sg
35 Kda Dystrophin-Associated Glycoprotein
35dag
Database Links Reactome: R-HSA-9913351
Cellular Localisation Cell Membrane
Sarcolemma
Single-Pass Type Ii Membrane Protein
Cytoplasm
Cytoskeleton
Alternative Protein Names Delta-Sarcoglycan protein
Delta-Sg protein
35 Kda Dystrophin-Associated Glycoprotein
35dag protein
SGCD protein

Information sourced from Uniprot.org

Citations

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