Human DEGS1 protein (Recombinant) (N-GST & C-His) (STJP010642)

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STJP010642
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Short Description :Recombinant-Human DEGS1-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:DEGS1
Gene ID:8560
Uniprot ID:DEGS1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ile230-Glu323
Post Translational Modifications Myristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels.
Function Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols.
Protein Name Sphingolipid Delta(4-Desaturase Des1
Cell Migration-Inducing Gene 15 Protein
Degenerative Spermatocyte Homolog 1
Dihydroceramide Desaturase-1
Membrane Lipid Desaturase
Retinol Isomerase
Database Links Reactome: R-HSA-1660661
Reactome: R-HSA-6798695
Cellular Localisation Mitochondrion Membrane
Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Sphingolipid Delta(4-Desaturase Des1 protein
Cell Migration-Inducing Gene 15 Protein protein
Degenerative Spermatocyte Homolog 1 protein
Dihydroceramide Desaturase-1 protein
Membrane Lipid Desaturase protein
Retinol Isomerase protein
DEGS1 protein
DES1 protein
MLD protein
MIG15 protein

Information sourced from Uniprot.org

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