Human DEGS1 protein (Recombinant) (N-GST & C-His) (STJP010642)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human DEGS1-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | DEGS1 |
| Gene ID | 8560 |
| Uniprot ID | DEGS1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ile230-Glu323 |
Additional Info
| Post Translational Modifications | Myristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels. |
| Function | Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols. |
| Protein Name | Sphingolipid Delta(4-Desaturase Des1Cell Migration-Inducing Gene 15 ProteinDegenerative Spermatocyte Homolog 1Dihydroceramide Desaturase-1Membrane Lipid DesaturaseRetinol Isomerase |
| Database Links | Reactome: R-HSA-1660661Reactome: R-HSA-6798695 |
| Cellular Localisation | Mitochondrion MembraneEndoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Sphingolipid Delta(4-Desaturase Des1 proteinCell Migration-Inducing Gene 15 Protein proteinDegenerative Spermatocyte Homolog 1 proteinDihydroceramide Desaturase-1 proteinMembrane Lipid Desaturase proteinRetinol Isomerase proteinDEGS1 proteinDES1 proteinMLD proteinMIG15 protein |
Information sourced from Uniprot.org