Human DEFB1 protein (Recombinant) (Tag free) (STJP014551)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human DEFB1-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 130mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | DEFB1 |
| Gene ID | 1672 |
| Uniprot ID | DEFB1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly22-Lys68 |
Additional Info
| Function | Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. |
| Protein Name | Beta-Defensin 1Bd-1Hbd-1Defensin - Beta 1 |
| Database Links | Reactome: R-HSA-1461957Reactome: R-HSA-1461973 |
| Cellular Localisation | SecretedMembraneAssociates With Tumor Cell Membrane-Derived Microvesicles |
| Alternative Protein Names | Beta-Defensin 1 proteinBd-1 proteinHbd-1 proteinDefensin - Beta 1 proteinDEFB1 proteinBD1 proteinHBD1 protein |
Information sourced from Uniprot.org