Human DEFa3 (Defensin Alpha 3, Neutrophil Specific) Sandwich ELISA Kit (STJE0008395)
SPECIFICATIONS
General Information
| Short Description | This DEFa3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 16.47pg/mL |
| Detection Limit | 46.8-3000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | DEFA3 |
| Gene ID | 1668 |
| Uniprot ID | DEF3_HUMAN |
| Sample Type | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B.anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Also blocks herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment. |
| Protein Name | Neutrophil Defensin 3Defensin - Alpha 3Hnp-3Hp-3Hp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2Hnp-2Hp-2Hp2 |
| Database Links | Reactome: R-HSA-1461973Reactome: R-HSA-1462054 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Neutrophil Defensin 3 ELISA kitDefensin - Alpha 3 ELISA kitHnp-3 ELISA kitHp-3 ELISA kitHp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2 ELISA kitHnp-2 ELISA kitHp-2 ELISA kitHp2 ELISA kitDEFA3 ELISA kitDEF3 ELISA kit |
| output |
Information sourced from Uniprot.org