Human DCNL4/DCUN1D4 protein (Recombinant) (His-Tag) (STJP018453)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DCNL4/DCUN1D4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT, 2mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DCUN1D4 |
| Gene ID | 23142 |
| Uniprot ID | DCNL4_HUMAN |
| Accession Number | NP_001035492 |
| Immunogen | Human |
| Immunogen Region | 1-292aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMHSDAAA VNFQLNSHLS TLANIHKIYH TLNKLNLTED IGQDDHQTGS LRSCSSSDCF NKVMPPRKKR RPASGDDLSA KKSRHDSMYR KYDSTRIKTE EEAFSSKRCL EWFYEYAGTD DVVGPEGMEK FCEDIGVEPE NVVMLVLAWK LDAQNMGYFT LQEWLKGMTS LQCDTTEKLR NTLDYLRSFL NDSTNFKLIY RYAFDFAR |
Additional Info
| Function | Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which are necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). |
| Protein Name | Dcn1-Like Protein 4Dcnl4Dcun1 Domain-Containing Protein 4Defective In Cullin Neddylation Protein 1-Like Protein 4 |
| Database Links | Reactome: R-HSA-8951664 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Dcn1-Like Protein 4 proteinDcnl4 proteinDcun1 Domain-Containing Protein 4 proteinDefective In Cullin Neddylation Protein 1-Like Protein 4 proteinDCUN1D4 proteinKIAA0276 protein |
Information sourced from Uniprot.org