Human DCK protein (Recombinant) (His-Tag) (STJP016878)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DCK-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 0.1mM PMSF, 2mM EDTA, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DCK |
| Gene ID | 1633 |
| Uniprot ID | DCK_HUMAN |
| Accession Number | NP_000779.1 |
| Immunogen | Human |
| Immunogen Region | 1-260aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Phosphorylated and activated in vitro upon phosphorylation at Ser-74 by CSNK1D/CK1. |
| Function | Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. |
| Protein Name | Deoxycytidine KinaseDckDeoxyadenosine KinaseDeoxyguanosine Kinase |
| Database Links | Reactome: R-HSA-73614Reactome: R-HSA-74217 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Deoxycytidine Kinase proteinDck proteinDeoxyadenosine Kinase proteinDeoxyguanosine Kinase proteinDCK protein |
Information sourced from Uniprot.org