Human DBP/GC protein (Recombinant) (N-His) (STJP003616)

Name: Human DBP/GC protein (Recombinant) (N-His) (STJP003616)
SKU: STJP003616
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP003616

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Short Description	Recombinant-Human DBP/GC-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Allele GC*1S is O-glycosylated at Thr-436. The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-mceeN-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated. The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated.
Function	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Protein Name	Vitamin D-Binding Protein Dbp Vdb Gc Protein-Derived Macrophage Activating Factor Gc-Maf Gcmaf Gc-Globulin Group-Specific Component Gc Vitamin D-Binding Protein-Macrophage Activating Factor Dbp-Maf
Database Links	Reactome: R-HSA-196791
Cellular Localisation	Secreted
Alternative Protein Names	Vitamin D-Binding Protein protein Dbp protein Vdb protein Gc Protein-Derived Macrophage Activating Factor protein Gc-Maf protein Gcmaf protein Gc-Globulin protein Group-Specific Component protein Gc protein Vitamin D-Binding Protein-Macrophage Activating Factor protein Dbp-Maf protein GC protein

Information sourced from Uniprot.org