Human DARS protein (Recombinant) (His-Tag) (STJP017577)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human DARS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 40% Glycerol, 0.15M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DARS1 |
| Gene ID | 1615 |
| Uniprot ID | SYDC_HUMAN |
| Accession Number | NP_001340 |
| Immunogen | Human |
| Immunogen Region | 1-501aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expression in the developing and adult brain shows similar patterns. Highly expressed in the ventricular and subventricular zones, including hippocampal subfields, the midlateral temporal cortex and the frontal polar cortex. The cerebellum, cerebral cortex, hippocampus, and lateral ventricle show preferential neuronal expression. Expression in the peripheral neurons is evident in the colon. |
| Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. |
| Protein Name | Aspartate--Trna Ligase - CytoplasmicAspartyl-Trna SynthetaseAsprsCell Proliferation-Inducing Gene 40 Protein |
| Database Links | Reactome: R-HSA-2408522Reactome: R-HSA-379716Reactome: R-HSA-9856649 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Aspartate--Trna Ligase - Cytoplasmic proteinAspartyl-Trna Synthetase proteinAsprs proteinCell Proliferation-Inducing Gene 40 Protein proteinDARS1 proteinDARS proteinPIG40 protein |
Information sourced from Uniprot.org