Human CYTH3 protein (Recombinant) (His-Tag) (STJP018754)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CYTH3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CYTH3 |
| Gene ID | 9265 |
| Uniprot ID | CYH3_HUMAN |
| Accession Number | NP_004218 |
| Immunogen | Human |
| Immunogen Region | 1-399aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMDEDGGG EGGGVPEDLS LEEREELLDI RRRKKELIDD IERLKYEIAE VMTEIDNLTS VEESKTTQRN KQIAMGRKKF NMDPKKGIQF LIENDLLQSS PEDVAQFLYK GEGLNKTVIG DYLGERDEFN IKVLQAFVEL HEFADLNLVQ ALRQFLWSFR LPGEAQKIDR MMEAFASRYC LCNPGVFQST DTCYVLSFAI IMLNTSLH |
Additional Info
| Tissue Specificity | Almost absent from liver, thymus and peripheral blood lymphocytes. |
| Function | Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization. |
| Protein Name | Cytohesin-3Arf Nucleotide-Binding Site Opener 3Protein Arno3General Receptor Of Phosphoinositides 1Grp1Ph - Sec7 And Coiled-Coil Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-6811438 |
| Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinCell JunctionAdherens JunctionTight JunctionTranslocates From The Cytosol To Membranes Enriched In Phosphatidylinositol 345-Trisphosphate |
| Alternative Protein Names | Cytohesin-3 proteinArf Nucleotide-Binding Site Opener 3 proteinProtein Arno3 proteinGeneral Receptor Of Phosphoinositides 1 proteinGrp1 proteinPh - Sec7 And Coiled-Coil Domain-Containing Protein 3 proteinCYTH3 proteinARNO3 proteinGRP1 proteinPSCD3 protein |
Information sourced from Uniprot.org