Human CYTH2 protein (Recombinant) (N-His) (STJP005876)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CYTH2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CYTH2 |
| Gene ID | 9266 |
| Uniprot ID | CYH2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Arg390 |
Additional Info
| Function | Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. Involved in neurite growth. |
| Protein Name | Cytohesin-2Arf Exchange FactorArf Nucleotide-Binding Site OpenerProtein ArnoPh - Sec7 And Coiled-Coil Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-6811438 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmCell ProjectionGrowth ConeCell JunctionTight JunctionAdherens JunctionBoth Isoform 1 And Isoform 2 Are Recruited To The Cell Membrane Through Its Association With Arl4aArl4c And Arl4dThey Require Also Interaction With Phosphoinositides For Targeting To Plasma MembraneIn Differentiating Neuroblastoma CellsColocalizes With Ccdc120 In Both Neurite Shaft And Growth Cone Areas |
| Alternative Protein Names | Cytohesin-2 proteinArf Exchange Factor proteinArf Nucleotide-Binding Site Opener proteinProtein Arno proteinPh - Sec7 And Coiled-Coil Domain-Containing Protein 2 proteinCYTH2 proteinARNO proteinPSCD2 proteinPSCD2L protein |
Information sourced from Uniprot.org