Human CYTH1 protein (Recombinant) (N-His) (STJP005449)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CYTH1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CYTH1 |
| Gene ID | 9267 |
| Uniprot ID | CYH1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-His398 |
Additional Info
| Post Translational Modifications | Ubiquitinated by SCF(FBXW11) E3 ubiquitin-protein ligase complex. Ubiquitination induces proteasomal degradation. |
| Function | Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. |
| Protein Name | Cytohesin-1Ph - Sec7 And Coiled-Coil Domain-Containing Protein 1Sec7 Homolog B2-1 |
| Database Links | Reactome: R-HSA-6811438 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmCytosolCell JunctionTight JunctionAdherens JunctionColocalized With Tjp1 During Epithelial Polarization |
| Alternative Protein Names | Cytohesin-1 proteinPh - Sec7 And Coiled-Coil Domain-Containing Protein 1 proteinSec7 Homolog B2-1 proteinCYTH1 proteinD17S811E proteinPSCD1 protein |
Information sourced from Uniprot.org