Human Cystatin SA protein (Recombinant) (STJP000398)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding Human Cystatin SA-CST2 (TRP21-ALA141) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Human Cystatin SA-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2ยฐC-8ยฐC C for one month, or at-20ยฐC to-70ยฐC for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/ยตg (1EU/ยตg). NA |
| Immunoreactivity | The activity was tested by the ability to inhibit Cathepsin L cleavage of a fluorogenic substrate. The ED50 was measured to be 10nM NA |
Target Information
| Gene Symbol | CST2 |
| Gene ID | 1470 |
| Uniprot ID | CYTT_HUMAN |
| Immunogen | Optimized DNA sequence encoding Human Cystatin SA-CST2 (TRP21-ALA141) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | TRP21-ALA141 |
Additional Info
| Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in submandibular gland and parotid gland. |
| Function | Thiol protease inhibitor. |
| Protein Name | Cystatin-SaCystatin-2Cystatin-S5 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cystatin-Sa proteinCystatin-2 proteinCystatin-S5 proteinCST2 protein |
Information sourced from Uniprot.org