| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Cystatin F-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
The activity was tested by the ability to inhibit Cathepsin L cleavage of a fluorogenic substrate. The ED50 was measured to < 7nM NA |
| Gene Symbol: |
CST7 |
| Gene ID: |
8530 |
| Uniprot ID: |
CYTF_HUMAN |
| Immunogen Region: |
ARG20-HIS145 |
| Immunogen: |
Optimized DNA sequence encoding Human Cystatin F-CST7 (ARG20-HIS145 ) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Primarily expressed in peripheral blood cells and spleen. |
| Function | Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system. |
| Protein Name | Cystatin-FCystatin-7Cystatin-Like Metastasis-Associated ProteinCmapLeukocystatin |
| Cellular Localisation | SecretedCytoplasm |
| Alternative Protein Names | Cystatin-F proteinCystatin-7 proteinCystatin-Like Metastasis-Associated Protein proteinCmap proteinLeukocystatin proteinCST7 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
