Name: Human Cystatin C protein (Recombinant) (His-Tag) (STJP018147)
SKU: STJP018147
Availability: InStock

Human Cystatin C protein (Recombinant) (His-Tag) (STJP018147)

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STJP018147

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Short Description :	Recombinant-Human Cystatin C-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	Enzyme Activity/SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	0.25 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Immunoreactivity:	The IC50 value is < 2.0nM. The inhibitory function of Cystatin 3 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.

Gene Symbol:	CST3
Gene ID:	1471
Uniprot ID:	CYTC_HUMAN
Accession Number:	NP_000090
Immunogen:	Human
Immunogen Region:	27-146aa
Immunogen Sequence:	MGSSHHHHHH SSGLVPRGSH MSSPGKPPRL VGGPMDASVE EEGVRRALDF AVGEYNKASN DMYHSRALQV VRARKQIVAG VNYFLDVELG RTTCTKTQPN LDNCPFHDQP HLKRKAFCSF QIYAVPWQGT MTLSKSTCQD A

Tissue Specificity	Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
Post Translational Modifications	The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
Function	As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
Protein Name	Cystatin-C Cystatin-3 Gamma-Trace Neuroendocrine Basic Polypeptide Post-Gamma-Globulin
Database Links	Reactome: R-HSA-381426 Reactome: R-HSA-6798695 Reactome: R-HSA-8957275 Reactome: R-HSA-977225
Cellular Localisation	Secreted
Alternative Protein Names	Cystatin-C protein Cystatin-3 protein Gamma-Trace protein Neuroendocrine Basic Polypeptide protein Post-Gamma-Globulin protein CST3 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP019256	Human Cystatin A protein (Recombinant) (His-Tag) (STJP019256)	E.coli	SDS-PAGE/Enzyme Activity
STJP017120	Human Cystatin A protein (Recombinant) (His-Tag) (STJP017120)	E.coli	SDS-PAGE
STJP017455	Human Cystatin SN protein (Recombinant) (His-Tag) (STJP017455)	E.coli	SDS-PAGE
STJP017644	Human Cystatin S protein (Recombinant) (His-Tag) (STJP017644)	E.coli	SDS-PAGE
STJP019257	Human Cystatin B protein (Recombinant) (His-Tag) (STJP019257)	E.coli	Enzyme Activity/SDS-PAGE

Human Cystatin C protein (Recombinant) (His-Tag) (STJP018147)

General Information