Human CXCL7 (Platelet Basic Protein) Antibody Pair (STJAP00203)
General Information
| Short Description | This CXCL7 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PPBP |
| Gene ID | 5473 |
| Uniprot ID | CXCL7_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human CXCL7 protein.Detection Immunogen: Recombinant Human CXCL7 protein. |
Additional Info
| Function | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. |
| Protein Name | Platelet Basic ProteinPbpC-X-C Motif Chemokine 7Leukocyte-Derived Growth FactorLdgfMacrophage-Derived Growth FactorMdgfSmall-Inducible Cytokine B7 Cleaved Into - Connective Tissue-Activating Peptide IiiCtap-IiiLa-Pf4Low-Affinity Platelet Factor Iv - Tc-2 - Connective Tissue-Activating Peptide Iii(1-81Ctap-Iii(1-81 - Beta-ThromboglobulinBeta-Tg - Neutrophil-Activating Peptide 2(74Nap-2(74 - Neutrophil-Activating Peptide 2(73Nap-2(73 - Neutrophil-Activating Peptide 2Nap-2 - Tc-1 - Neutrophil-Activating Peptide 2(1-66Nap-2(1-66 - Neutrophil-Activating Peptide 2(1-63Nap-2(1-63 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Platelet Basic Protein antibody pairPbp antibody pairC-X-C Motif Chemokine 7 antibody pairLeukocyte-Derived Growth Factor antibody pairLdgf antibody pairMacrophage-Derived Growth Factor antibody pairMdgf antibody pairSmall-Inducible Cytokine B7 Cleaved Into - Connective Tissue-Activating Peptide Iii antibody pairCtap-Iii antibody pairLa-Pf4 antibody pairLow-Affinity Platelet Factor Iv - Tc-2 - Connective Tissue-Activating Peptide Iii(1-81 antibody pairCtap-Iii(1-81 - Beta-Thromboglobulin antibody pairBeta-Tg - Neutrophil-Activating Peptide 2(74 antibody pairNap-2(74 - Neutrophil-Activating Peptide 2(73 antibody pairNap-2(73 - Neutrophil-Activating Peptide 2 antibody pairNap-2 - Tc-1 - Neutrophil-Activating Peptide 2(1-66 antibody pairNap-2(1-66 - Neutrophil-Activating Peptide 2(1-63 antibody pairNap-2(1-63 antibody pairPPBP antibody pairCTAP3 antibody pairCXCL7 antibody pairSCYB7 antibody pairTGB1 antibody pairTHBGB1 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human CXCL7 (Platelet Basic Protein) Antibody Pair (STJAP00203)
This antibody pair detects human CXCL7, also known as Platelet Basic Protein (UniProt P02775). Reactivity has been confirmed for human samples only.
The capture antibody is an unconjugated mouse monoclonal antibody and the detection antibody is a biotin-conjugated goat polyclonal antibody. Both are supplied at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair has been validated for use in ELISA. It is intended for research use only and is not validated for diagnostic or therapeutic applications.
Both the capture and detection antibodies were raised against recombinant human CXCL7 protein. The capture antibody was purified using Protein A or G, while the detection antibody was purified by antigen affinity.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.