Human CXCL3/GRO-gamma/MIP2-beta protein (Recombinant) (No tag) (STJP001397)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human CXCL3/GRO-gamma/MIP2-beta Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala35-Asn107) of human CXCL3/GRO gamma (Accession #NP_002081.2) fused with no additional amino acid.
General Information
| Short Description | Recombinant-Human CXCL3/GRO-gamma/MIP2-beta-No tag protein was developed in e.coli using the region Ala35-Asn107. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <1 EU/Mu g |
Target Information
| Gene Symbol | CXCL3 |
| Gene ID | 2921 |
| Uniprot ID | CXCL3_HUMAN |
| Immunogen | Recombinant Human CXCL3/GRO-gamma/MIP2-beta Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala35-Asn107) of human CXCL3/GRO gamma (Accession #NP_002081.2) fused with no additional amino acid. |
| Immunogen Region | Ala35-Asn107 |
| Immunogen Sequence | ASVVTELRCQCLQTLQGIHL KNIQSVNVRSPGPHCAQTEV IATLKNGKKACLNPASPMVQ KIIEKILNKGSTN |
Additional Info
| Function | Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. |
| Protein Name | C-X-C Motif Chemokine 3Gro-Gamma(1-73Growth-Regulated Protein GammaGro-GammaMacrophage Inflammatory Protein 2-BetaMip2-Beta Cleaved Into - Gro-Gamma(5-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-X-C Motif Chemokine 3 proteinGro-Gamma(1-73 proteinGrowth-Regulated Protein Gamma proteinGro-Gamma proteinMacrophage Inflammatory Protein 2-Beta proteinMip2-Beta Cleaved Into - Gro-Gamma(5-73 proteinCXCL3 proteinGRO3 proteinGROG proteinSCYB3 protein |
Information sourced from Uniprot.org