Human CXCL2/MIP-2 protein (Recombinant) (No-Tag) (STJP003012)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human CXCL2/MIP-2 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Ala35-Asn107) of Human CXCL2/MIP-2 (Accession #NP_002080.1) fused with No tag.
General Information
| Short Description | Recombinant-Human CXCL2/MIP-2-No-Tag protein was developed in hek293 cells using the region Ala35-Asn107. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of 20mMTris, 500mMNaCl, pH 8.0 |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CXCL2 |
| Gene ID | 2920 |
| Uniprot ID | CXCL2_HUMAN |
| Immunogen | Recombinant Human CXCL2/MIP-2 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Ala35-Asn107) of Human CXCL2/MIP-2 (Accession #NP_002080.1) fused with No tag. |
| Immunogen Region | Ala35-Asn107 |
| Immunogen Sequence | LRSSSQNSSDKPVAHVVANH QAEEQLEWLSQRANALLANG MDLKDNQLVVPADGLYLIYS QVLFKGQGCPDYVLLTHTVS RFAISYQEKVSLLSAIKSPC PKDTPEGAELKPWYEPMYLG GVFQLEKGDLLSAEVNLPKY LDITESGQVYFGVIAL |
Additional Info
| Post Translational Modifications | The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. |
| Function | Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. |
| Protein Name | C-X-C Motif Chemokine 2Growth-Regulated Protein BetaGro-BetaMacrophage Inflammatory Protein 2-AlphaMip2-Alpha Cleaved Into - Gro-Beta(5-73Gro-Beta-THematopoietic Synergistic FactorHsfSb-251353 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-X-C Motif Chemokine 2 proteinGrowth-Regulated Protein Beta proteinGro-Beta proteinMacrophage Inflammatory Protein 2-Alpha proteinMip2-Alpha Cleaved Into - Gro-Beta(5-73 proteinGro-Beta-T proteinHematopoietic Synergistic Factor proteinHsf proteinSb-251353 proteinCXCL2 proteinGRO2 proteinGROB proteinMIP2A proteinSCYB2 protein |
Information sourced from Uniprot.org