Human CXCL17/DMC/VCC1 protein (Recombinant) (N-GST) (STJP005602)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CXCL17/DMC/VCC1-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CXCL17 |
| Gene ID | 284340 |
| Uniprot ID | CXL17_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu24-Leu119 |
Additional Info
| Post Translational Modifications | Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion. |
| Function | Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17: Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. |
| Protein Name | C-X-C Motif Chemokine 176-Cys Cxcl17Dendritic Cell And Monocyte Chemokine-Like ProteinDmcVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-X-C Motif Chemokine 17 protein6-Cys Cxcl17 proteinDendritic Cell And Monocyte Chemokine-Like Protein proteinDmc proteinVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 proteinCXCL17 proteinVCC1 proteinUNQ473 proteinPRO842 protein |
Information sourced from Uniprot.org