Human CXCL16/SR-PSOX protein (Recombinant) (C-His) (STJP020131)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human CXCL16/SR-PSOX Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Thr205) of Human CXCL16/SR-PSOX Protein (Accession #NP_001094282.1) fused with His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human CXCL16/SR-PSOX-C-His protein was developed in hek293 cells using the region Met1-Thr205. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CXCL16 |
| Gene ID | 58191 |
| Uniprot ID | CXL16_HUMAN |
| Immunogen | Recombinant Human CXCL16/SR-PSOX Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Thr205) of Human CXCL16/SR-PSOX Protein (Accession #NP_001094282.1) fused with His tag at the C-terminus. |
| Immunogen Region | Met1-Thr205 |
| Immunogen Sequence | MGRDLRPGSRVLLLLLLLLL VYLTQPGNGNEGSVTGSCYC GKRISSDSPPSVQFMNRLRK HLRAYHRCLYYTRFQLLSWS VCGGNKDPWVQELMSCLDLK ECGHAYSGIVAHQKHLLPTS PPISQASEGASSDIHTPAQM LLSTLQSTQRPTLPVGSLSS DKELTRPNETTIHTAGHSLA AGPEAGENQKQPEKNAGPTA RTSAT |
Additional Info
| Tissue Specificity | Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow. |
| Post Translational Modifications | Glycosylated. |
| Function | Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. |
| Protein Name | C-X-C Motif Chemokine 16Scavenger Receptor For Phosphatidylserine And Oxidized Low Density LipoproteinSr-PsoxSmall-Inducible Cytokine B16Transmembrane Chemokine Cxcl16 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSecretedAlso Exists As A Soluble Form |
| Alternative Protein Names | C-X-C Motif Chemokine 16 proteinScavenger Receptor For Phosphatidylserine And Oxidized Low Density LipoproteinSr-Psox proteinSmall-Inducible Cytokine B16 proteinTransmembrane Chemokine Cxcl16 proteinCXCL16 proteinSCYB16 proteinSRPSOX proteinUNQ2759 proteinPRO6714 protein |
Information sourced from Uniprot.org