Human CXCL16 protein (Recombinant) (C-His) (STJP013579)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CXCL16-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CXCL16 |
| Gene ID | 58191 |
| Uniprot ID | CXL16_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn30-Thr205 |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. |
| Protein Name | C-X-C Motif Chemokine 16Scavenger Receptor For Phosphatidylserine And Oxidized Low Density LipoproteinSr-PsoxSmall-Inducible Cytokine B16Transmembrane Chemokine Cxcl16 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSecretedAlso Exists As A Soluble Form |
| Alternative Protein Names | C-X-C Motif Chemokine 16 proteinScavenger Receptor For Phosphatidylserine And Oxidized Low Density LipoproteinSr-Psox proteinSmall-Inducible Cytokine B16 proteinTransmembrane Chemokine Cxcl16 proteinCXCL16 proteinSCYB16 proteinSRPSOX proteinUNQ2759 proteinPRO6714 protein |
Information sourced from Uniprot.org