Human CXCL1/GRO-alpha protein (Recombinant) (No-tag NA) (STJP001996)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human CX CL1/GRO-alpha Protei n is produced by E. coli expression syst em. The target prote in is expressed with sequence ( Ala35-As n107) of Human CXCL1/GRO-alpha (Accessio n #NP_001502.1) fuse d with No-tag.
General Information
| Short Description | Recombinant-Human CXCL1/GRO-alpha-No-tag protein was developed in e.coli using the region Ala35-As n107. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CXCL1 |
| Gene ID | 2919 |
| Uniprot ID | GROA_HUMAN |
| Immunogen | Recombinant Human CX CL1/GRO-alpha Protei n is produced by E. coli expression syst em. The target prote in is expressed with sequence ( Ala35-As n107) of Human CXCL1/GRO-alpha (Accessio n #NP_001502.1) fuse d with No-tag. |
| Immunogen Region | Ala35-As n107 |
| Immunogen Sequence | ASVATELRCQCLQTLQGIHP KNIQSVNVKSPGPHCAQTEV IATLKNGRKACLNPASPIVK KIIEKMLNSDKSN |
Additional Info
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
| Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Gro-Alpha(1-73Melanoma Growth Stimulatory ActivityMgsaNeutrophil-Activating Protein 3Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Growth-Regulated Alpha Protein proteinC-X-C Motif Chemokine 1 proteinGro-Alpha(1-73 proteinMelanoma Growth Stimulatory Activity proteinMgsa proteinNeutrophil-Activating Protein 3 proteinNap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 proteinCXCL1 proteinGRO proteinGRO1 proteinGROA proteinMGSA proteinSCYB1 protein |
Information sourced from Uniprot.org